Multi-Channel Local Binary Pattern Guided Convolutional Neural Network for Breast Cancer Classification

The advancement in convolutional neural network (CNN) has reduced the burden of experts using the computer-aided diagnosis of human breast cancer. However, most CNN networks use spatial features only. The inherent texture structure present in histopathological images plays an important role in distinguishing malignant tissues. This paper proposes an alternate CNN network that integrates Local Binary Pattern (LBP) based texture information with CNN features.

The study propagates that LBP provides the most robust rotation, and translation-invariant features in comparison with other texture feature extractors. Therefore, a formulation of LBP in context of convolution operation is presented and used in the proposed CNN network. A non-trainable fixed set binary convolutional filters representing LBP features are combined with trainable convolution filters to approximate the response of the convolution layer. A CNN architecture guided by LBP features is used to classify the histopathological images.

The network is trained using BreKHis datasets. The use of a fixed set of LBP filters reduces the burden of CNN by minimizing training parameters by a factor of 9. This makes it suitable for the environment with fewer resources. The proposed network obtained 96.46% of maximum accuracy with 98.51% AUC and 97% F1-score.

LBP based texture information plays a vital role in cancer image classification. A multi-channel LBP futures fusion is used in the CNN network. The experiment results propagate that the new structure of LBP-guided CNN requires fewer training parameters preserving the capability of the CNN network’s classification accuracy.