Aims and Scope

The Open Biomedical Engineering Journal is an Open Access online journal which publishes original research articles, reviews/mini-reviews, letters and guest edited single topic issues in all areas of biomedical engineering. The journal focuses on the original high-quality multidisciplinary research in the field of biosystems, including biomedical modeling; cell and tissue engineering for repair medicine; biomeasurements, biosignal processing and biosensing systems; artificial and bioartificial organs; biomaterials; biomechanics and rehabilitation, medical information systems and neuronal networks; brain-computer interfaces, communication technologies in medicine, medical imaging including brain functional magnetic resonance imaging (fMRI), genome analysis, medical physics, bioinformatics, biophotonics and optical tomography.


The Open Biomedical Engineering Journal, a peer reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality articles rapidly and freely available to researchers worldwide.


Recent Articles

In vitro Biomodels in Stenotic Arteries to Perform Blood Analogues Flow Visualizations and Measurements: A Review

Violeta Carvalho, Inês Maia, Andrews Souza, João Ribeiro, Pedro Costa, H. Puga, Senhorinha Teixeira, Rui A. Lima

Cardiovascular diseases are one of the leading causes of death globally and the most common pathological process is atherosclerosis. Over the years, these cardiovascular complications have been extensively studied by applying in vivo, in vitro and numerical methods (in silico). In vivo studies represent more accurately the physiological conditions and provide the most realistic data. Nevertheless, these approaches are expensive, and it is complex to control several physiological variables. Hence, the continuous effort to find reliable alternative methods has been growing. In the last decades, numerical simulations have been widely used to assess the blood flow behavior in stenotic arteries and, consequently, providing insights into the cardiovascular disease condition, its progression and therapeutic optimization. However, it is necessary to ensure its accuracy and reliability by comparing the numerical simulations with clinical and experimental data. For this reason, with the progress of the in vitro flow measurement techniques and rapid prototyping, experimental investigation of hemodynamics has gained widespread attention. The present work reviews state-of-the-art in vitro macro-scale arterial stenotic biomodels for flow measurements, summarizing the different fabrication methods, blood analogues and highlighting advantages and limitations of the most used techniques.


December 31, 2020
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Editor's Choice

In vitro Biomodels in Stenotic Arteries to Perform Blood Analogues Flow Visualizations and Measurements: A Review

Violeta Carvalho, Inês Maia, Andrews Souza, João Ribeiro, Pedro Costa, H. Puga, Senhorinha Teixeira, Rui A. Lima

Cardiovascular diseases are one of the leading causes of death globally and the most common pathological process is atherosclerosis. Over the years, these cardiovascular complications have been extensively studied by applying in vivo, in vitro and numerical methods (in silico). In vivo studies represent more accurately the physiological conditions and provide the most realistic data. Nevertheless, these approaches are expensive, and it is complex to control several physiological variables. Hence, the continuous effort to find reliable alternative methods has been growing. In the last decades, numerical simulations have been widely used to assess the blood flow behavior in stenotic arteries and, consequently, providing insights into the cardiovascular disease condition, its progression and therapeutic optimization. However, it is necessary to ensure its accuracy and reliability by comparing the numerical simulations with clinical and experimental data. For this reason, with the progress of the in vitro flow measurement techniques and rapid prototyping, experimental investigation of hemodynamics has gained widespread attention. The present work reviews state-of-the-art in vitro macro-scale arterial stenotic biomodels for flow measurements, summarizing the different fabrication methods, blood analogues and highlighting advantages and limitations of the most used techniques.


December 31, 2020
READ MORE

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