Aims and Scope
Recent Articles
In vitro Biomodels in Stenotic Arteries to Perform Blood Analogues Flow Visualizations and Measurements: A Review
Violeta Carvalho, Inês Maia, Andrews Souza, João Ribeiro, Pedro Costa, H. Puga, Senhorinha Teixeira, Rui A. Lima
Cardiovascular diseases are one of the leading causes of death globally and the most common pathological process is atherosclerosis. Over the years, these cardiovascular complications have been extensively studied by applying in vivo, in vitro and numerical methods (in silico). In vivo studies represent more accurately the physiological conditions and provide the most realistic data. Nevertheless, these approaches are expensive, and it is complex to control several physiological variables. Hence, the continuous effort to find reliable alternative methods has been growing. In the last decades, numerical simulations have been widely used to assess the blood flow behavior in stenotic arteries and, consequently, providing insights into the cardiovascular disease condition, its progression and therapeutic optimization. However, it is necessary to ensure its accuracy and reliability by comparing the numerical simulations with clinical and experimental data. For this reason, with the progress of the in vitro flow measurement techniques and rapid prototyping, experimental investigation of hemodynamics has gained widespread attention. The present work reviews state-of-the-art in vitro macro-scale arterial stenotic biomodels for flow measurements, summarizing the different fabrication methods, blood analogues and highlighting advantages and limitations of the most used techniques.
December 31, 2020
Articles
- December 21, 2020
An Integrated Hardware and Software Application to Support Wound Measurement Using a 3D Scanner and Image Processing Techniques
October 23, 2020Temperature Influences at the Myoelectric Level in the Upper Extremities of the Human Body
April 23, 2020Numerical Computational Study of Photoacoustic Signals from Eye Models to Detect Diabetic Retinopathy
March 20, 2020A Standard Protocol Proposal for Reliable and Time-Saving Shielding Effectiveness Measurements for MRI Faraday Cages
October 15, 2020Simulation of Bronchial Airflow in COPD Patients
October 26, 2020MU-LapaRobot: A Corporative Surgical Robot for Laparoscopic Surgery
Editor's Choice
In vitro Biomodels in Stenotic Arteries to Perform Blood Analogues Flow Visualizations and Measurements: A Review
Violeta Carvalho, Inês Maia, Andrews Souza, João Ribeiro, Pedro Costa, H. Puga, Senhorinha Teixeira, Rui A. Lima
Cardiovascular diseases are one of the leading causes of death globally and the most common pathological process is atherosclerosis. Over the years, these cardiovascular complications have been extensively studied by applying in vivo, in vitro and numerical methods (in silico). In vivo studies represent more accurately the physiological conditions and provide the most realistic data. Nevertheless, these approaches are expensive, and it is complex to control several physiological variables. Hence, the continuous effort to find reliable alternative methods has been growing. In the last decades, numerical simulations have been widely used to assess the blood flow behavior in stenotic arteries and, consequently, providing insights into the cardiovascular disease condition, its progression and therapeutic optimization. However, it is necessary to ensure its accuracy and reliability by comparing the numerical simulations with clinical and experimental data. For this reason, with the progress of the in vitro flow measurement techniques and rapid prototyping, experimental investigation of hemodynamics has gained widespread attention. The present work reviews state-of-the-art in vitro macro-scale arterial stenotic biomodels for flow measurements, summarizing the different fabrication methods, blood analogues and highlighting advantages and limitations of the most used techniques.
December 31, 2020