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Characterization of Liposomes for Cancer Cell Transfection
The Open Biomedical Engineering Journal
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26 Oct 2007 •
RESEARCH ARTICLE
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DOI: 10.2174/1874120700701010060
Abstract
We have characterized a broad range of liposome formulations with varying DcChol:DOPE ratio. Subsequent addition of DcChol to liposomes increases its positive surface charge. However, loading the nuclear acids did not neutralize the overall negative surface potential to a similar extent. The liposomes were tested by transfection of DNA in living cancer cells.
