Research on the Influence of Anti-fatigue Effect and Movement Ability of Blueberry Polysaccharides on Aged Mice
Identifiers and Pagination:Year: 2015
First Page: 314
Last Page: 317
Publisher Id: TOBEJ-9-314
Article History:Received Date: 26/05/2015
Revision Received Date: 14/07/2015
Acceptance Date: 10/08/2015
Electronic publication date: 19/10/2015
Collection year: 2015
open-access license: This is an open access articles licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided that the work is properly cited.
The article introduces functions as well as extraction and purification of polysaccharides, and the effect of blueberry polysaccharides (BPs) on movement endurance, anti-fatigue capacity and related physiological indexes in aged mice induced by D-galactose is going to be investigated. The method of water extract-alcohol precipitation is used in the experiment to extract polysaccharides from blueberries, and in-vitro oxidation resistance and bacteriostasis of polysaccharides are studied after preliminary purification so as to provide a reference for the production and application of blueberry polysaccharides. Mice are randomly divided into a normal control group, an aged model group, a BP low-dose group, a BP medium-dose group, and a BP high-dose group. After the administration of BPs for 20 consecutive days, the exhaustive swimming time and fatigue indexes are determined. The results show that BPs could prolong the exhaustive swimming time, decrease the content of BUN, BLA and MDA, and obviously increase the activity of HG, MG, SOD and LDH. To conclude, BPs have good anti-fatigue effect. This study may provide theoretical evidence for the development of anti-fatigue drugs from BPs.